Top 14 Best Decongestant Nose Spray In 2024

Offers immediate relief from nasal congestion due to colds and even allergies without causing drowsiness.

Its pharmacist recommended formula opens your nose and even your sinus openings by shrinking the swollen nasal membranes.

Temporarily relieves congestion due to common cold, hay fever, and other respiratory allergies

Decongestant nose drops help clear nasal passages and shrinks swollen membranes

Temporarily restores freer breathing through the nose and helps decongest sinus openings and passages

Contains no alcohol, pseudoephedrine, artificial dyes or parabens

Safe for use in children ages 2 years and up

Contains 4 bottles of Little Remedies Decongestant Nose Drops, 0.5 fl oz each

FSA- and HSA-eligible product in the U.S.

Targets nasal congestion and sinus pressure at the source by reducing swelling in the sinuses

Breathe better all day or all night long with Vicks Sinex Severe; For instant; 12-hour; nasal congestion and sinus pressure relief

This powerful decongestant medicine be used to treat severe sinus congestion and pressure caused by a cold or seasonal allergy spell; Not intended for daily use

Unlike nasal decongestant tablets; Vicks Sinex Severe Nasal Sprays works by delivering powerful decongestant medicine directly to your nasal membranes

Vicks Sinex Severe Nasal Spray is HSA and FSA eligible; Check with your provider for more details

Targets nasal congestion and sinus pressure at the source by reducing swelling in the sinuses

Breathe better all day or all night long with Vicks Sinex Severe; For instant; 12-hour; nasal congestion and sinus pressure relief

This powerful decongestant medicine be used to treat severe sinus congestion and pressure caused by a cold or seasonal allergy spell; Not intended for daily use

Unlike nasal decongestant tablets; Vicks Sinex Severe Nasal Sprays works by delivering powerful decongestant medicine directly to your nasal membranes

Vicks Sinex Severe Nasal Spray is HSA and FSA eligible; Check with your provider for more details

NATURAL SALINE SOLUTION & NASAL RINSE: Our nasal saline spray will gently clean and moisturize the sinus tissues. Unlike other normal saline nasal sprays our spray can also decongest the sinuses by targeting the primary causes of nasal congestion. Our nose spray will help reduce tissue swelling from pollen, pollution, contaminants, and other irritants.

SAFE NASAL RINSE & SPRAY: Our all-natural nasal cleaner is safe for kids, non-addictive, Non-GMO Project Verified and is effective without the use of steroids, drugs, or chemicals. It is the ideal daily sinus medicine that will reduce swelling and open your airways. Using our saline nose spray before bed may reduce snoring.

IMPROVED FORMULA WITH XYLITOL: Our patented saline nasal spray solution may reduce tissue inflammation and naturally open airways. Xylitol's powerful oral and upper respiratory health benefits come from its unique five-carbon structure. Xylitol may help reduce swelling and allergy symptoms by reducing contaminant adhesion on your nasal tissue.

EASY TO USE DIRECTIONS: Clear the nasal passageway by gently blowing your nose before using Xlear. Prime the pump by holding the sinus rinse bottle upright and pumping one or more times until the saline solution is dispensed. Insert nozzle into nostril and depress pump completely while breathing in through your nose. Spray each nostril 2-4 times and use at least twice daily.

WASH AWAY POLLUTANTS: Our natural saline nasal spray can wash away pollutants and help to bring sinus relief. Use our sinus spray daily to protect and keep your nasal passages clean. Each 1.5 oz bottle delivers approx. 240 fine mist Sprays so you can find fast and quick relief.

INSTANT RELIEF. Includes oxymetazoline for instant relief from even the most extreme congestion and sinus pressure.

INCLUDES XYLITOL. The addition of xylitol cleans, moisturizes, and protects delicate sinus tissues.

12-HOUR RELIEF. Patented formula provides a full 12 hours of relief without drowsiness or dryness.

EASY-TO-USE PUMP SPRAY. Metered pump sprayer ensures precise dosing every time.

NATURAL INGREDIENTS. Over 99% natural formula containing just 4 ingredients means you know exactly what’s going up your nose.

SINUS & ALLERGY RELIEF: Mucinex Sinus-Max Severe Nasal Congestion Relief helps relieve nasal congestion, sinus congestion and sinus pressure

# 1 TRUSTED COLD BRAND: #1 Cold brand doctors trust*

COOLING MENTHOL BURST: With an instant cooling menthol burst

NASAL DECONGESTANT: Contains Oxymetazoline HCl, a topical nasal decongestant

FAST ACTING RELIEF: Targeted Nasal Congestion relief

DOSING: Offers fast and long-lasting nasal congestion relief up to 12 hours

USAGE: Use as directed; For ages 6+ years

NATURAL SINUS RELIEF & NASAL RINSE: Xlear Max nasal spray with xylitol will gently clean and moisturize the sinus tissues while providing congestion relief. Unlike other normal saline nasal sprays, our xylitol nasal saline spray acts as a nasal cleaner that washes away severe sinus pressure and congestion by targeting the primary causes of nasal congestion. Our nose spray will help reduce tissue swelling from pollen, pollution, contaminats, and other irritants.

STRONGER FORMULA WITH CAPSICUM & XYLITOL: Our patented nasal spray solution reduces swollen tissue and naturally opens airways. With added Capsicum our nasal spray features contaminant blocking and antihistamine properties to help ward off stuffiness before it even starts. Xylitol's powerful oral and upper respiratory health benefits come from its unique five-carbon structure. Xylitol helps to reduce swelling and allergy symptoms by reducing contaminant adhesion on your nasal tissue.

SAFE NASAL RINSE & SPRAY: Our all-natural nasal cleaner is safe for kids, non-addictive and non-GMO Project Verified and is effective without the use of steroids, drugs or chemicals. It’s the ideal sinus spray that will reduce swelling and open your airways. Use our saline nose spray before bed to help alleviate congestion that causes snoring.

WASH AWAY POLLUTANTS: Our natural saline nasal spray will wash away pollutants and help to bring relief to chronic sinus issues. Use our sinus spray daily to protect and keep your nasal passages clean and hydrated. Each 1.5 oz bottle delivers approximately 180 fine mist sprays so you can find fast and quick relief.

EASY TO USE DIRECTIONS: Clear the nasal passageway by gently blowing your nose before using Xlear. Prime the pump by holding the sinus rinse bottle upright and pumping one or more times until the solution is dispensed. Insert nozzle into nostril and depress pump completely while breathing in through your nose. Spray each nostril 1-2 times. Use as needed.

ACTIVE INGREDIENT: This nasal spray contains oxymetazoline hydrochloride 0.05%, a nasal decongestant. Compare to the active ingredient in Afrin Original

PURPOSE: This nasal spray temporarily relieves nasal congestion, sinus congestion and pressure due to the common cold, hay fever and upper respiratory allergies

12 HOUR RELIEF: GoodSense Maximum Strength Nasal Spray provides fast, powerful congestion relief for allergies and colds for up to 12 hours

FAST CONGESTION RELIEF: Provides fast and powerful nasal congestion relief for allergies and colds

FAST-ACTING NASAL DECONGESTANT clears stuffy nose due to upper respiratory allergies and the common cold

ACTIVE INGREDIENT: Amazon Basic Care Nasal Four Nasal Spray contains phenylephrine hydrochloride 1%, a nasal decongestant, which compares to the active ingredient in 4-Way.

FAST-ACTING NASAL SPRAY: Amazon Basic Care Nasal Four Nasal Spray contains a nasal decongestant that delivers fast relief of nasal congestion for up to four hours.

MULTI-SYMPTOM RELIEF: Amazon Basic Care Nasal Four Nasal Spray relieves nasal congestion, swollen nasal membranes, sinus congestion and sinus pressure.

NON-DROWSY NASAL CONGESTION RELIEF: Amazon Basic Care Nasal Four Nasal Spray provides non-drowsy relief for nasal symptoms so that you can get through your day.

FOR AGES 12 YEARS AND OLDER: Amazon Basic Care Nasal Four Nasal Spray provides fast nasal congestion relief for adults and children ages 12 years and older.

Targets nasal congestion and sinus pressure at the source by reducing swelling in the sinuses

Breathe better all day or all night long with Vicks Sinex Severe. For instant, 12-hour, nasal congestion and sinus pressure relief

This powerful decongestant medicine be used to treat severe sinus congestion and pressure caused by a cold or seasonal allergy spell, Not intended for daily use

Unlike nasal decongestant tablets, Vicks Sinex Severe Nasal Sprays works by delivering powerful decongestant medicine directly to your nasal membranes

Vicks Sinex Severe Nasal Spray is HSA and FSA eligible, Check with your provider for more details

12 hour nasal relief

severe congestion

compare to afrin severe congestion

pump mist

anti-drip

NASAL SPRAY DECONGESTANT offers immediate and effective sinus and allergy relief. Nose spray is a quick and easy OTC method for sinus pressure relief and nasal decongestion.

STUFFY NOSE RELIEF Whether it’s cat allergies that have you stuffy, or the common cold, experience powerful and rapid 12 hour relief with Reliable-1’s nose spray.

COLD AND ALLERGY RELIEF Compact size of our nasal spray is ideal for taking on the go, so you’ll never be slowed down by the common cold or a sudden allergy attack. Keep the anti drip nose spray in your purse, glove compartment or briefcase for quick and easy access, whenever you need it.

NOSE SPRAY ACTIVE INGREDIENT Compare to Active Ingredient in Afrin Original. 2-3 sprays with pump mist sinus spray clears the nasal passages for temporary congestion relief and easier breathing.

RELIABLE 1 Reliable 1 Laboratories is an Over the Counter (OTC) and Nutritional Supplement provider with a leadership team holding 100+ years of experience. Providing you with quality products that best address your family’s health is our priority.